State-of-the-Art Lectures

The Leon Schiff State-of-the-Art Lecture*

Goals and Objectives:

• Recoginize the signs and symptoms of acute liver failure (ALF).
• Discuss the varying etiologies of acute liver failure and their differing clinical presentations.
• Be able to plan a workup and considerations for initial treatment and for transplantation.
• Understand issues surrounding determination of prognosis and outcomes in ALF.

The Leon Schiff State-of-the-Art Lecture honors Dr. Schiff and recognizes the work he did to elevate the study and practice of hepatology to the discipline it is today. The restricted fund supporting this lecture ensures that future hepatologists will have a district platform from which to provide their valuable insights at The Liver Meeting®. AASLD greatly acknowledges the National Genetics Institute for its generous support of this fund.

The Thomas E. Starzl Transplant Surgery State-of-the-Art Lecture*

Goals and Objectives:

• Review clinical and animal transplant models of liver-related tolerance.
• Examine possible mechanisms to explain tolerance induced by the liver.
• Propose potential clinical scenarios for application of liver tolerance.

Hymann J. Zimmerman Hepatotoxicity State-of-the-Art Lecture *

Goals and Objectives:

• Describe how manipulation of genetic circuits controlled by nuclear receptors can alter metabolism leading to new ways to control obesity and enhance physical performance.

Hans Popper Basic Science State-of-the-Art Lecture *

Goals and Objectives:

• Present a synthesis of the remarkable recent discoveries of the various roles of small RNAs in normal and disease processes.
• Outline the potential development of small RNAs as therapeutic agents to modify disease processes.

The Hans Popper Basic Science State-of-the-Art lecture recognizes Hand Popper, the founder of AASLD, his role in the establishment of the AASLD journal HEPATOLOGY, and his promotion of the intellectual spirit of the Association.

Presentation Title	Presenter
Hyman Zimmerman Hepatotoxicity State-of-the-Art Lecture: Nuclear Receptors and Liver Disease –Vitamin D D’Livers	Ronald M. Evans, PhD
Thomas E. Starzl Transplant Surgery State-of-the-Art Lecture: Hepatic Tolerance	John J. Fung, MD, PhD
Leon Schiff State-of-the-Art Lecture: Acute Liver Failure	William M. Lee, MD
Hans Popper State-of-the-Art: Insulin Resistance	Gerald I. Shulman, MD, PhD

*The Leon Schiff State-of-the-Art Lecture honors Dr. Schiff and recognizes the work he did to elevate the study and practice of hepatology to the discipline it is today. The restricted fund supporting this lecture ensures that future hepatologists will have a district platform from which to provide their valuable insights at The Liver Meeting®. AASLD greatly acknowledges the National Genetics Institute for its generous support of this fund.

*The Thomas E. Starzl Transplant Surgery State-of-the-Art Lecture recognizes the pioneering work that Dr. Thomas E. Starzl and colleagues have done to elevate liver transplantation from an experimental procedure to one that saves thousands of lives annually. To ensure that future transplant scientists have a distinct platform to provide their valuable insights at The Liver Meeting®, a restricted fund has been established to support this lecture in perpetuity. AASLD gratefully acknowledges the following individuals and organizations that have generously contributed to this fund:

AASLD
Astellas Pharma US, Inc.
Ted Bader, MD
Clyde F. Barker, MD
Adel Bozorgzadeh, MD
Pradip Chakrabarti, MD
Chao-Long Chen, MD
David K. C. Cooper, MD
Bijan Eghtesad, MD
Ira J. Fox, MD
John J. Fung, MD
Ashokkumar B. Jain, MD
Zakiyah Kadry, MD
Dympna Kelly, MD
Charles M. Miller, MD
Ernesto P. Molmenti, MD
Michael C. Morris, MD
Eduardo A. Santiago-Delpin, MD
Byers W. Shaw, Jr., MD
Cynthia A. Smetanka, MD
Lewis Teperman, MD
Paul Terasaki, MD

*The Hyman J. Zimmerman Hepatotoxicity State-of-the-Art Lecture recognizes Dr. Zimmerman’s work in toxic liver injury. A restricted fund supporting this lecture ensures that future investigators will have a distinct platform to present their valuable work on liver toxicity at The Liver Meeting®. AASLD gratefully acknowledges Eli Lilly and Company for its generous support of this fund.

*The Hans Popper Basic Science State-of-the-Art lecture recognizes Hand Popper, the founder of AASLD, his role in the establishment of the AASLD journal HEPATOLOGY, and his promotion of the intellectual spirit of the Association.