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AASLD News: July 29, 2010

Hepatology Table of Contents 
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Hepatology

Volume 52 Issue 2 (August 2010)

Comments from the Editors
Efficacy, effectiveness, and comparative effectiveness in liver disease (p 403-407)
Hashem B. El-Serag, Jayant Talwalkar, W. Ray Kim
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Editorial
New insights into the role of iron in the development of nonalcoholic fatty liver disease (p 408-410)
Paul A. Sharp
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Viral Hepatitis
Involvement of PA28gamma in the propagation of hepatitis C virus (p 411-420)
Kohji Moriishi, Ikuo Shoji, Yoshio Mori, Ryosuke Suzuki, Tetsuro Suzuki, Chikako Kataoka, Yoshiharu Matsuura
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Amino acid substitution in hepatitis C virus core region and genetic variation near the interleukin 28B gene predict viral response to telaprevir with peginterferon and ribavirin (p 421-429)
Norio Akuta, Fumitaka Suzuki, Miharu Hirakawa, Yusuke Kawamura, Hiromi Yatsuji, Hitomi Sezaki, Yoshiyuki Suzuki, Tetsuya Hosaka, Masahiro Kobayashi, Mariko Kobayashi, Satoshi Saitoh, Yasuji Arase, Kenji Ikeda, Kazuaki Chayama, Yusuke Nakamura, Hiromitsu Kumada
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Evaluation of depression as a risk factor for treatment failure in chronic hepatitis C (p 430-435)
Peter Derek Christian Leutscher, Martin Lagging, Mads Rauning Buhl, Court Pedersen, Gunnar Norkrans, Nina Langeland, Kristine Mørch, Martti Färkkilä, Simon Hjerrild, Kristoffer Hellstrand, Per Bech, for the NORDynamIC Group
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The impact of hepatitis C virus infection on work absence, productivity, and healthcare benefit costs (p 436-442)
Jun Su, Richard A. Brook, Nathan L. Kleinman, Patricia Corey-Lisle
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Transcriptome sequencing, microarray, and proteomic analyses reveal cellular and metabolic impact of hepatitis C virus infection in vitro (p 443-453)
Stephen D. Woodhouse, Ramamurthy Narayan, Sally Latham, Sheena Lee, Robin Antrobus, Bevin Gangadharan, Shujun Luo, Gary P. Schroth, Paul Klenerman, Nicole Zitzmann
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Early on-treatment prediction of response to peginterferon alfa-2a for HBeAg-negative chronic hepatitis B using HBsAg and HBV DNA levels (p 454-461)
Vincent Rijckborst, Bettina E. Hansen, Yilmaz Cakaloglu, Peter Ferenci, Fehmi Tabak, Meral Akdogan, Krzysztof Simon, Ulus S. Akarca, Robert Flisiak, Elke Verhey, Anneke J. Van Vuuren, Charles A. B. Boucher, Martijn J. ter Borg, Harry L. A. Janss
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Steatohepatitis/Metabolic Liver Disease
Hepatic iron loading in mice increases cholesterol biosynthesis (p 462-471)
Ross M. Graham, Anita C. G. Chua, Kim W. Carter, Roheeth D. Delima, Daniel Johnstone, Carly E. Herbison, Martin J. Firth, Rebecca O'Leary, Elizabeth A. Milward, John K. Olynyk, Debbie Trinder
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High-dose ursodeoxycholic acid therapy for nonalcoholic steatohepatitis: a double-blind, randomized, placebo-controlled trial (p 472-479)
Ulrich F. H. Leuschner, Birgit Lindenthal, Günter Herrmann, Joachim C. Arnold, Martin Rössle, Hans-Jörg Cordes, Stefan Zeuzem, Jasper Hein, Thomas Berg, the NASH Study Group
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Hepatobiliary Malignancies
c-Jun mediates hepatitis C virus hepatocarcinogenesis through signal transducer and activator of transcription 3 and nitric oxide-dependent impairment of oxidative DNA repair (p 480-492)
Keigo Machida, Hidekazu Tsukamoto, Jian-Chang Liu, Yuan-Ping Han, Sugantha Govindarajan, Michael M. C. Lai, Shizuo Akira, Jing-hsiung James Ou
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Thiazolidinediones inhibit hepatocarcinogenesis in hepatitis B virus-transgenic mice by peroxisome proliferator-activated receptor gamma-independent regulation of nucleophosmin (p 493-505)
Andrea Galli, Elisabetta Ceni, Tommaso Mello, Simone Polvani, Mirko Tarocchi, Francesca Buccoliero, Francesca Lisi, Laura Cioni, Barbara Ottanelli, Valeria Foresta, Guido Mastrobuoni, Gloriano Moneti, Giuseppe Pieraccini, Calogero Surrenti, Stefano Milani
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Synergistic role of sprouty2 inactivation and c-Met up-regulation in mouse and human hepatocarcinogenesis (p 506-517)
Susie A. Lee, Sara Ladu, Matthias Evert, Frank Dombrowski, Valentina De Murtas, Xin Chen, Diego F. Calvisi
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Effect of aging on risk for hepatocellular carcinoma in chronic hepatitis C virus infection (p 518-527)
Yasuhiro Asahina, Kaoru Tsuchiya, Nobuharu Tamaki, Itsuko Hirayama, Tomohiro Tanaka, Mitsuaki Sato, Yutaka Yasui, Takanori Hosokawa, Ken Ueda, Teiji Kuzuya, Hiroyuki Nakanishi, Jun Itakura, Yuka Takahashi, Masayuki Kurosaki, Nobuyuki Enomoto, Namiki Izumi
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Octamer 4 (Oct4) mediates chemotherapeutic drug resistance in liver cancer cells through a potential Oct4-AKT-ATP-binding cassette G2 pathway (p 528-539)
Xiao Qi Wang, Weg M. Ongkeko, Lin Chen, Zhen Fan Yang, Ping Lu, Kwok Kin Chen, Jay P. Lopez, Ronnie T.P. Poon, Sheung Tat Fan
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Molecular characterization of the vascular features of focal nodular hyperplasia and hepatocellular adenoma: A role for angiopoietin-1 (p 540-549)
Annette S. H. Gouw, Wenjiao Zeng, Marijke Buiskool, Inge Platteel, Marius C. van den Heuvel, Sibrand Poppema, Koert P. de Jong, Grietje Molema
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A smac mimetic reduces TNF Related Apoptosis Inducing Ligand (TRAIL)-induced invasion and metastasis of cholangiocarcinoma cells (p 550-561)
Christian D. Fingas, Boris R. A. Blechacz, Rory L. Smoot, Maria E. Guicciardi, Justin Mott, Steve F. Bronk, Nathan W. Werneburg, Alphonse E. Sirica, Gregory J. Gores
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Autoimmune, Cholestatic and Biliary Disease
The specificity of fatigue in primary biliary cirrhosis: Evaluation of a large clinic practice (p 562-570)
Nadya Al-Harthy, Teru Kumagi, Catalina Coltescu, Gideon M. Hirschfield
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Incidence and prevalence of primary sclerosing cholangitis in a defined adult population in sweden (p 571-577)
Björn Lindkvist, Maria Benito de Valle, Bo Gullberg, Einar Björnsson
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Liver Failure/Cirrhosis/Portal Hypertension
Association between serum uric acid level and chronic liver disease in the United States (p 578-589)
Anita Afzali, Noel S. Weiss, Edward J. Boyko, George N. Ioannou
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Endothelial cell toll-like receptor 4 regulates fibrosis-associated angiogenesis in the liver (p 590-601)
Kumaravelu Jagavelu, Chittaranjan Routray, Uday Shergill, Steven P. O'Hara, William Faubion, Vijay H. Shah
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Liver Injury/Regeneration
Cytosolic calcium regulates liver regeneration in the rat (p 602-611)
Laura Lagoudakis, Isabelle Garcin, Boris Julien, Kis Nahum, Dawidson A. Gomes, Laurent Combettes, Michael H. Nathanson, Thierry Tordjmann
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Liver Biology/Pathobiology
Human immunodeficiency virus (HIV)-1 infects human hepatic stellate cells and promotes collagen I and monocyte chemoattractant protein-1 expression: Implications for the pathogenesis of HIV/hepatitis C virus-induced liver fibrosis (p 612-622)
Ana C. Tuyama, Feng Hong, Yedidya Saiman, Chuansheng Wang, Derya Ozkok, Arevik Mosoian, Ping Chen, Benjamin K. Chen, Mary E. Klotman, Meena B. Bansal
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Lipid rafts are essential for peroxisome biogenesis in HepG2 cells (p 623-633)
Jannes Woudenberg, Krzysztof P. Rembacz, Mark Hoekstra, Antonella Pellicoro, Fiona A. J. van den Heuvel, Janette Heegsma, Sven C. D. van IJzendoorn, Andreas Holzinger, Tsuneo Imanaka, Han Moshage, Klaas Nico Faber
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Quantifying growth and transformation frequency of oncogene-expressing mouse hepatocytes in vivo (p 634-643)
Marxa L. Figueiredo, Kristin M. Wentworth, Eric P. Sandgren
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Cytosolic phospholipase A2alpha and peroxisome proliferator-activated receptor gammasignaling pathway counteracts transforming growth factor beta-mediated inhibition of primary and transformed hepatocyte (p 644-655)
Chang Han, William C. Bowen, Guiying Li, Anthony J. Demetris, George K. Michalopoulos, Tong Wu
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Glycosylation of fibroblast growth factor receptor 4 is a key regulator of fibroblast growth factor 19-mediated down-regulation of cytochrome P450 7A1 (p 656-666)
Vassilis Triantis, Eirikur Saeland, Nora Bijl, Ronald P. Oude-Elferink, Peter L. M. Jansen
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Biliary secretion of S-nitrosoglutathione is involved in the hypercholeresis induced by ursodeoxycholic acid in the normal rat (p 667-677)
Carlos M. Rodríguez-Ortigosa, Jesús M. Banales, Israel Olivas, Iker Uriarte, José J.G. Marín, Fernando J. Corrales, Juan F. Medina, Jesús Prieto
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Transgenic expression of cholesterol 7alpha-hydroxylase in the liver prevents high-fat diet-induced obesity and insulin resistance in mice (p 678-690)
Tiangang Li, Erika Owsley, Michelle Matozel, Peter Hsu, Colleen M. Novak, John Y. L. Chiang
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CXC receptor-2 knockout genotype increases X-linked inhibitor of apoptosis protein and protects mice from acetaminophen hepatotoxicity (p 691-702)
Bin Hu, Lisa M. Colletti
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Carbonyl reductase 1 as a novel target of (-)-epigallocatechin gallate against hepatocellular carcinoma (p 703-714)
Weixue Huang, Liya Ding, Qiang Huang, Hairong Hu, Shan Liu, Xianmei Yang, Xiaohui Hu, Yongjun Dang, Suqin Shen, Jie Li, Xiaona Ji, Songmin Jiang, Jun O. Liu, Long Yu
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Special Articles
What is critical for liver surgery and partial liver transplantation: Size or quality? (p 715-729)
Pierre-Alain Clavien, Christian E. Oberkofler, Dimitri A. Raptis, Kuno Lehmann, Andreas Rickenbacher, Ashraf Mohammad El-Badry
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Meeting Report
Standardization of nomenclature and causality assessment in drug-induced liver injury: Summary of a clinical research workshop (p 730-742)
Robert J. Fontana, Leonard B. Seeff, Raúl J. Andrade, Einar Björnsson, Christopher P. Day, Jose Serrano, Jay H. Hoofnagle
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Diagnostic and Therapeutic Advances in Hepatology
Drug Therapy: Tenofovir (p 743-747)
Anna S. F. Lok
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Reviews
Pharmacogenetics of drug-induced liver injury (p 748-761)
Stefan Russmann, Alexander Jetter, Gerd A. Kullak-Ublick
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Loco-regional treatment of hepatocellular carcinoma (p 762-773)
Riccardo Lencioni
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Hepatic lipotoxicity and the pathogenesis of nonalcoholic steatohepatitis: The central role of nontriglyceride fatty acid metabolites (p 774-788)
Brent A. Neuschwander-Tetri
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Hepatology Elsewhere
Vitamin E for nonalcoholic steatohepatitis: Ready for prime time? (p 789-792)
Jean-François F. Dufour
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Gut instinct: Rifaximin for the prevention of hepatic encephalopathy (p 792-794)
Asma Siddique, Kris Kowdley
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Image of the Month
An unusual cause of acute cholangitis (p 795-796)
Rabin Rahmani, Elena Ivanina, Lina Yang
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Correspondence
ldquoNonalcoholic fatty liver diseaserdquo in a developing country: A different perspective (p 797)
Sujoy Maitra
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Reply: (p 797-798)
Kshaunish Das, Abhijit Chowdhury
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Antituberculosis therapy drug-induced liver injury and acute liver failure (p 798-799)
Harshad Devarbhavi, Ross Dierkhising, Walter K. Kremers
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Reply: (p 799-800)
Subrat Kumar Acharya
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Transient elastography in the early prediction of progressive recurrent hepatitis C following liver transplantation (p 800-801)
Cristina Rigamonti, Maria Francesca Donato, Massimo Colombo
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Targeting heme oxygenase/adiponectin axis for chronic hepatitis C treatment (p 801)
Federico Salamone, Giovanni Li Volti
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The curative efficiency of tenofovir for patients with chronic hepatitis B after failure of nucleoside/nucleotide analogues (p 802)
En-Qiang Chen, Hong Tang
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Hepatitis B in refugees, guessing the prevalence (p 802-803)
Jose Daniel Debes
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Is cigarette smoking an independent risk factor or a cofactor for nonalcoholic fatty liver disease? (p 803-804)
Cheng-Fu Xu, Chao-Hui Yu, Lei Xu, Min Miao, You-Ming Li
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Histological subclassification of cirrhosis (p 805)
Giacomo Germani, Amar Dhillon, Lorenzo Andreana, Vincenza Calvaruso, Penelopi Manousou, Graziella Isgró, Andrew Kenneth Burroughs
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